Historians believe that Uganda's northeastern districts were inhabited by herders migrating from the east over a period of several centuries. Their twentieth-century descendants live in Kenya, Sudan, and Uganda, where the largest groups are the Karamojong (people of Karamoja) ethnic groups. These include the Karamojong proper, as well as Jie, Dodoth, and several small related groups, constituting about 12 percent of the population. All Karamojong peoples speak almost the same language (Akaramojong), with different pronunciations. The Iteso (people of Teso) south of Karamoja also speak an Eastern Nilotic language (Ateso) and are historically related to the Karamojong, but the Iteso are sometimes classified separately, based on cultural differences (many of which are recently acquired). The small Teuso (Ik), Tepeth, and Labwor populations in the northeast also speak Eastern Nilotic languages but maintain separate cultural identities. In northwestern Uganda, the Kakwa are also classified as Eastern Nilotic, based on linguistic similarities to the Karamojong, despite the fact that Kakwa society is surrounded by Western Nilotic and Central Sudanic language speakers.

Data as of December 1990